| Course Info · Lecture and Lab Schedule · Grading · Syllabus.pdf · Blackboard | Links |
Lectures and Labs: Principles of Genetics BIOL 362The below schedule is subject to daily change. Assignments and handouts will be added as the class progresses.Check back frequently, and remember to reload this page every time you visit! |
Date | Lecture Topic | Reading | Week | Lab activities | |||||
| Fri. | Sept 4 | Introduction Handout, Slides | Ch 1 | ||||||
| Mon. | Sept 7 | Labor Day, no class | Sept 7-9 | No lab this week | |||||
| Wed. | Sept 9 | Chromosomes and cellular reproduction Handout, Slides Cell Cycle, Meiosis, Genetic variation and meiosis,Genetic variation and meiosis | Ch 2, p.13-34 | ||||||
| Fri. | Sept 11 | Principles of heredity Handout, Slides | Ch 3, p.43-56 | ||||||
| Mon. | Sept 14 | Principles of heredity Handout, Slides Mendelian Genetics Overview Science is Real | Ch 3, p. 62-64; Ch 4, p.81-82,84-87; Ch 5, p.99-104 | Sept 14-16 | Lab 1: | Meiosis & Mitosis Computer Flies 1 Fly lab logon Lab Report 2-4 pages due next week in lab on one set of fly crosses (not one in lab handout) | |||
| Wed. | Sept 16 | 2 loci (different chromosomes) Handout, Slides | Ch 3, p.57-65 | ||||||
| Fri. | Sept 18 | Gene interactions, Epistasis Handout, Slides | Ch 5, p.105-115 | ||||||
| Mon. | Sept 21 | Genetic linkage Handout, Slides | Ch 7, p. 160-170 | Sept 21-23 | Lab 2: | Computer Flies 2 Fly lab logon Identify Drosophila mutants | |||
| Wed. | Sept 23 | Genetic linkage cont, Non-Mendelian Inheritance Handout, Slides | Ch 7, p. 160-175; Ch 5 p. 115-120 | ||||||
| Fri. | Sept 25 | Extensions of basic principles | Ch 5, p.115-120,122-123 | ||||||
| Mon. | Sept 28 | Pedigrees Handout, Slides | Ch 6 | Sept 28-30 | Lab 3: | Computer Flies 3 Fly lab logon Genetic Disease introduction Genetic Counselor | |||
| Wed. | Sept 30 | Review/Catchup | |||||||
| Thurs. | Oct 1 | Review Session 5pm Bunnell 308 | |||||||
| Fri. | Oct 2 | Exam 1 Study Guide Old Exams | |||||||
| Mon. | Oct 5 | Mapping Handout, Slides Mapping with 3 point tetstcross | Ch 7, p.173-185,188-189 | Oct 5-7 | Lab 4: | Fruit DNA extraction Pipette techniques and safety | |||
| Wed. | Oct 7 | Mapping Handout, Slides | Ch 3 | ||||||
| Fri. | Oct 9 | Mapping Handout, Slides | Ch 24 | ||||||
| Mon. | Oct 12 | Quantitative Genetics, QTLs Handout, Slides Read about heritability | Ch 24 | Oct 12-14 | Lab 5: | DNA extraction-plants Genetic Disease Presentations (group project) | |||
| Wed. | Oct 14 | Quantitative Genetics, QTLs Handout, Slides | Ch 24 | ||||||
| Fri. | Oct 16 | Quantitative Genetics,PCR Handout, Slides | Ch 24 | ||||||
| Mon. | Oct 19 | DNA replication, pcr Handout, Slides DNA replication - simplePCR1, PCR2 | Ch19 p.513-515 | Oct 19-21 | Lab 6: | PCR DNA replication | |||
| Wed. | Oct 21 | QTLs, molecular markers Handout, Slides, Electrophoresis | Ch 24 | ||||||
| Fri. | Oct 23 | QTLs, hapmap Handout, Slides, Microarray basics Microarray Method for Genetic Testing - Detailed Watch lab processes for high throughput microarray processing HapMap Haplotypes HapMap Wikepedia | Ch 24 | ||||||
| Mon. | Oct 26 | Review/Catchup, midterm evaluations | Oct 26-28 | Lab 7: | Gel of PCR PCR cleanup 23 and Me Handout DNA Diary 23 and me | ||||
| Tue. | Oct 27 | Review Session 5pm Bunnell 308 | |||||||
| Wed. | Oct 28 | Exam 2 Study Guide Old Exams | |||||||
| Fri. | Oct 30 | DNA sequencing Handout, Slides, Sanger Sequencing | |||||||
| Mon. | Nov 2 | Chromosomes Handout, Slides, Heterozygous Chromosome Inversion effect on meiosis Heterozygous inversion effect on meiosis Robertsonian Translocation | Ch 9 | Nov 2-4 | Lab 8: | WRRB tour Meet in Elvey Entrance area DNA sequencing | |||
| Wed. | Nov 4 | Chromosomes Handout, Slides, Gene duplications and evolution of new functions Click on "8-09 Evolution of homologous genes" | Ch 9 | ||||||
| Fri. | Nov 6 | Chromosomes Handout, Slides, Mistakes in Meiosis | Ch 9 | ||||||
| Mon. | Nov 9 | transposable elements Handout, Slides, Cut and paste transposition - click on "simple transposition" Copy and Paste transposition (replicative transposition) | Ch 11 | Nov 9-11 | Lab 9: | Quiz on DNA sequencing and PCR and reading Reading to discuss in lab: The second coming of gene therapy Chromosome rearrangements | |||
| Wed. | Nov 11 | transposable elements Handout, Slides, Transcription and translation Transcription and translation 2 Viral reverse transcription McClintock and Ac Ds transposons" | Ch 11 | ||||||
| Fri. | Nov 13 | Bacterial transformation Handout, Slides, Restriction enzyme and ligating insert into plasmid Bacterial transformation Click on "18-02 Steps in cloning a gene" Plant transformation Click on "19-08 Genes into plants using the Ti plasmid" Gene Gun Gene gun 2 | |||||||
| Mon. | Nov 16 | Shotgun sequencing Handout, Slides, genomic DNA library Shotgun sequencing | Nov 16-18 | Lab 10: | Bacterial Transformation Shotgun sequencing activity Jaberwocky genome Quiz on transposable elements and bacterial transformation (read handout) | ||||
| Wed. | Nov 18 | DNA packing Handout, Slides, DNA packing 1 DNA packing 2 DNA packing 3 histone deacetylation | Ch 11 | ||||||
| Fri. | Nov 20 | Genome size, centromeres, telomeres Handout, Slides, Telomerase 1 Telomerase 2 Telomerase 3 Nobel prize for telomeres and telomerase | |||||||
| Mon. | Nov 23 | Review/Catchup | Nov 23-25 | Lab 11: | No lab this week | ||||
| Tue | Nov 24 | Review Session 5pm Bunnell 408 (lab room) | |||||||
| Wed. | Nov 25 | Exam 3 Study Guide Old Exams | |||||||
| Fri. | Nov 27 | Thanksgiving Holiday, no class | Ch 19 | ||||||
| Mon. | Nov 30 | DNA sequence analysis | Nov 30-2 | Sequence Analysis [download MEGA software] [Class Data] [Class Sequence Alignment in mega file] [Arabidopsis Alignment in mega file] Check transformation results | |||||
| Wed. | Dec 2 | Genomics and proteomics | |||||||
| Fri. | Dec 4 | Genomics and proteomics | |||||||
| Mon. | Dec 7 | Organelle DNA | Dec 7-9 | Lab 12: | Gene Therapy | ||||
| Wed. | Dec 9 | Epigenetics | |||||||
| Fri. | Dec 11 | Epigenetics Epigenetics information Epigenetics video Epigenetics web site, Epigenetics in Discover Magazine, 1hr Nova Epigenetics Video Epigenetics Review Paper | |||||||
| Mon. | Dec 14 | Review/Catchup | Dec 14-16 | No lab this week | |||||
| Wed. | Dec 16 | 10:15-12:15 Final Exam (half on new material, half cumulative) Study Guide Old Exams |
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Instructor contact information:
Diana Wolf |
